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[Introduction of Scientific and Technological Achievements] Brain Invigorating Instrument
As the saying goes, "to live a long life, first raise your brain, raise your brain for a hundred years"
The Institute of Biomedicine and equipment of our hospital (hereinafter referred to as "Biomedicine Institute") has such a product, which can help us strengthen the brain, raise the brain and delay brain aging. Let's take a look at this magic product and the powerful technology behind it.
The scope of brain health is very wide, almost all encephalopathy and some sub-health states caused by the nervous system belong to the category of brain health imbalance. Nowadays, in real life, many middle-aged and elderly people, as well as young people, may eventually lead to brain health damage or Alzheimer's disease (Alzheimer's disease) due to long-term irrational use of the brain or bad living habits.
Alzheimer's disease
Alzheimer's disease (Alzheimer's Disease, AD) is a progressive cognitive dysfunction and memory impairment as the main performance, and is closely related to aging of the central nervous system degenerative diseases. With the aging of the population and the changes in people's diet and living habits, the number of AD patients is increasing sharply. According to ADI(Alzheimer's Disease International) statistics, as of 2015, there are about 46.8 million dementia patients in the world, of which there are about 6 million in China, ranking first in the world. It is estimated that by 2050, the number of people suffering from the disease will exceed 0.131 billion.
Source: Chinese Journal of General Practitioners
Clinical manifestations of AD patients
mild dementia stage
It is characterized by memory loss, oblivion of recent events, decreased judgment ability, less verbal vocabulary and difficulty in naming.
moderate dementia stage
Far and near memory is severely impaired, and the visual spatial ability of simple structures is reduced; calculation is impossible; Aphasia, apraxia, and agnosia are visible.
severe dementia stage
Completely dependent on caregivers, with only fragments of memory; unable to take care of themselves in daily life; primitive reflexes such as strong grip, groping and sucking.
In recent years, many breakthroughs have been made in the pathogenesis of AD, and many hypotheses have been proposed, such as Aβ cascade theory, oxidative stress theory, Tau protein theory, central cholinergic nerve injury theory, genetic factors theory, chronic inflammation theory, excitatory amino acid toxicity theory.
However, so far, the most important thing is the Aβ cascade theory: abnormal secretion of Aβ and its oligomers → irreversible dense senile plaques → metabolic disorder of neurons → disruption of ion balance inside and outside the membrane leading to abnormal phosphorylation and distribution of Tau protein → formation of neurofibrillary tangles → neuronal apoptosis → finally inducing hippocampal synaptic plasticity impairment → cognitive and learning and memory function decline.
Alzheimer's pathology model based on experimental evidence
The previous study of the Institute of Biomedicine in our hospital found that the level of Aβ is directly related to the distribution and status of cerebrospinal fluid. Direct injection of cerebrospinal fluid from the fourth ventricle into the lateral ventricle can reduce the level of Aβ in neurons in this area and improve the lesion. The relative position of the fourth ventricle and the lateral ventricle is physically changed, which can promote the exchange of cerebrospinal fluid in the region, reduce the level of Aβ in hippocampal neurons, and improve the phenotype of Alzheimer's disease.
pattern of cerebrospinal fluid circulation
Based on the above research, the Institute of Biomedicine designed and developed a brain-building instrument. The brain-strengthening instrument is an adjustable reciprocating auxiliary motion device with cervical spine as the axis. At the same time, there are transcranial magnetic stimulation (adjustable intensity) and far-infrared wavelength temperature therapy (adjustable temperature) with specific frequency at the head cushion. Through position change, transcranial magnetic stimulation and far-infrared temperature therapy act on brain tissue and cerebrospinal fluid in multiple ways to promote the degradation of IDE to Aβ toxic protein, it plays a role in strengthening the brain, delaying brain aging, and improving the health of the brain of ordinary people, especially in improving the phenotype of Alzheimer's disease and reducing the occurrence of brain aging-related diseases.
Schematic diagram of the principle of brain-strengthening instrument
Simply put, the IDE in our brain is the most effective "main force" to reduce Aβ toxic protein. However, with age, the level of IDE in different positions of the brain decreases and is unevenly distributed, which makes the IDE in the hippocampus of the learning and memory center unable to degrade Aβ toxic protein and is damaged. The mechanical movement of the brain-strengthening instrument can transport the IDE from other parts, which can effectively promote the degradation of IDE and eliminate Aβ toxic protein. At the same time, transcranial magnetic stimulation and far-infrared wavelength temperature therapy have a good role in promoting the degradation of Aβ toxic protein, which can be said to be the "right arm" of IDE. The joint efforts of the three make Aβ toxic protein invisible and protect your brain health. Simply put, the IDE in our brain is the most effective "main force" to reduce Aβ toxic protein. However, with age, the level of IDE in different positions of the brain decreases and is unevenly distributed, which makes the IDE in the hippocampus of the learning and memory center unable to degrade Aβ toxic protein and is damaged. The mechanical movement of the brain-strengthening instrument can transport the IDE from other parts, which can effectively promote the degradation of IDE and eliminate Aβ toxic protein. At the same time, transcranial magnetic stimulation and far-infrared wavelength temperature therapy have a good role in promoting the degradation of Aβ toxic protein, which can be said to be the "right arm" of IDE. The joint efforts of the three make Aβ toxic protein invisible and protect your brain health.
Advantages of brain-invigorating instrument
1、
Complete physical therapy, no pain, no side effects, to the user to play the greatest degree of protection, prevention and treatment.
2、
Multi-level and multi-means for targeted treatment of pathogenic factors, greatly improving the efficiency of treatment.
3、
The economic cost is significantly lower than the current clinical treatment methods.
4、
The whole device is simple in structure and easy to operate.
5、
Brain health care, delay brain aging, prevent brain diseases.
Brain-invigorating instrument
Patients with Alzheimer's disease or other dementias bear huge pressure on medical and care expenditures every year. This brain-strengthening instrument can reduce the financial burden of the patient's family, but more importantly, it is for patients. Brought the dawn of recovery and brought hope to their families.
In addition to improving the cognitive level of Alzheimer's disease and other dementia patients, it is also of great benefit to ordinary people!
1. The change of head position makes the brain move up, which has the effect of relieving brain fatigue and strengthening the brain;
2. The neck in the head movement to get the maximum degree of stretch, to relax the cervical spine and relieve the role of neck muscles;
3. For mental workers, especially IT, finance, lawyers, office staff and other practitioners, play a role in restoring brain power and preventing brain aging;
Mechanical exercise + transcranial magnetic stimulation + far infrared thermotherapy = brain health
This is the powerful technology behind the brain machine!
Strong science and technology comes from an excellent team. Relying on the strong scientific research force and advanced technology of Tsinghua University School of Medicine and School of Pharmacy, the Institute of Biomedicine mainly focuses on four research and development directions with the policy support of Tianjin Municipal People's Government and the strong support of Tsinghua University High-end Equipment Research Institute, namely health and medical equipment, drugs and diagnostic reagents, green mildew prevention and preservation, functional food and health products, etc. The director of the institute is Professor Wang Zhao from the School of Pharmacy of Tsinghua University. The team's research and development fields involve life sciences, biomedicine, clinical medicine, medical equipment, bio-related fluid mechanics and mechanical design, food safety, etc., and has a number of patents.
Technical docking and business negotiation
Contact: Wu Guibin
Mobile phone: 15320129639
Tel: 022-84856480
Email: wugb@tsinghua-tj.org
Source | Institute of Biomedicine and Equipment
Editor | Zhang Shu
The final interpretation right of the above related technologies belongs to the Institute of Biomedicine and Equipment.
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Tianjin High-end Equipment Research Institute, Tsinghua University, Copyright
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